High Performing Viral Vaccine Production Media Additives

You are having trouble optimizing your virus production system.

You are looking for better chemically-defined media.

InVitria has the solution.

High performance virus production can be a challenge for your research and vaccine production requirements.

Whether you are using mammalian cell lines or other virus production systems, the need for consistent and high yielding cultures is a top priority. And, it is critical to utilize a well-defined and animal component-free media for development and production. The benefits are seen in both financial savings and an efficient regulatory process.

Many cell lines used for live virus production and vaccines, such as Vero and HEK 293, can be difficult to culture. This makes it difficult to consistently produce a high live virus titre. The challenges you may be trying to address include:

• Poor host cell growth
• Increased host cell apoptosis
• Poor cell adherence to microcarriers
• Low viral yield and inadequate live virus production
• Lack of performance from chemically-defined media
• Inconsistent cell performance and viral yield between lots

The Solution:

High Performance Media Additives from InVitria

InVitria's scientists have developed new animal-free media additives that perform well when replacing animal components or as performance enhancing additives for chemically-defined media in a viral vaccine production system. The superior cell culture media supplements offered by InVitria:

• Maximize growth of many mammalian cell lines, including Vero and HEK 293
• Increase host cell adherence to microcarriers
• Optimize live virus production and live virus titre
• Increase cell viability and density while stabilizing the virus
• Are chemically-defined and well-characterized supplements
• Ensure lot-to-lot consistency
• Are free of animal or blood derivatives, such as bovine serum albumin (BSA)
• Regulatory-friendly

It is vital for both human vaccines and animal vaccines to be developed using a safe, high- yield and consistent live virus production process.

InVitria's Cellastim^TM, Cellastim^TM cGMP and Albumin-VAX are animal-free, regulatory-friendly and well-defined media additives for any live virus production or vaccine production system. They also consistently improve cell line growth and live virus titre while maintaining a chemically-defined media.

Cellastim^TM

Cellastim^TM recombinant human albumin is specifically developed to enhance cell culture performance in media, including a chemically-defined and animal component-free medium. Cellastim^TM can improve performance for cell lines previously adapted to media containing animal components such as serum, BSA or plasma-derived HSA. Cellastim^TM is well defined and complies with regulatory standards.

Click here to learn more about Cellastim^TM, including pricing.

Cellastim^TM cGMP

Cellastim^TM complies with FDA required current good manufacturing processes (cGMP), which ensures product safety and purity of both human vaccines and animal vaccines.

Click here to learn more about Cellastim^TM cGMP, including pricing.

Albumin-VAX

Albumin-VAX is an alternative used when replacing bovine albumin (BSA) and plasma-derived human serum albumin (pHSA) in animal vaccines. It eliminates safety concerns and significantly improves cell growth in animal vaccine production systems.

Click here to learn more about Albumin-VAX, including pricing.

InVitria's media additives:

• Enhance microcarrier cell growth in a wide variety of cell lines
• Allow more efficient infection of cells, propagation and live virus production
• Increase efficiency and cost effectiveness of vaccine biomanufacturing process
• Boost productivity while reducing apoptosis
• Perform as well as BSA when replacing bovine albumin

Addressing all the major concerns in cell line development today, InVitria's products are set to revolutionize laboratories around the world. Let us show you!