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Stem Cells, Regenerative Medicine-Growth Optimization Needed

Stem cells are notoriously difficult to maintain and grow.


You are looking for ways to improve your stem cell culture.


Now you CAN enhance your stem cell culture growth!

Stem cells from umbilical cords, bone marrow or embryos are cultured in vitro to produce specialized, differentiated cells such as muscle, heart or nerve cells. These adaptable stems cells and other primary cells such as keratinocytes, fibroblasts, osteoblasts and many others are used in regenerative medicine. They are also used for tissue transplantation, medical therapies to treat diseases like leukemia, and in basic research.

Culturing Stem Cells Can Be Problematic

Stem and primary cells have many uses, but they are not usually easy cells to maintain or grow. They are generally grown in medium containing fetal bovine serum (FBS), bovine serum albumin (BSA), human serum albumin (HSA), or knock-out serum replacement (KSR).

Some scientists avoid animal or human-derived components in cell culture media due to problems. The common problems encountered include:

  • Variability with animal-derived serums like FBS, HSA and KSR
  • Increased risk of infection of the stem cell culture, creating regulatory issues, particularly when cells are grown for patient transplants

• Altered stem cell morphology, growth and apoptosis

• Difficulty keeping stem cells in undifferentiated state

The Solution to Problems with Stem Cell Culture

Stem cells, research on regenerative medicine and transplantation is too important to let these problems continue. Optimize your stem cell culture by adding these animal-free products from InVitria to your media:

Recombinant human serum albumin (rHSA, or CellastimTM)

Recombinant human lactoferrin (rhLF or LacrominTM)

Recombinant human transferrin (hTF or OptiferrinTM)

InVitria focuses on maximizing stem cells, regenerative medicine and transplantation. This is done by delivering products that improve performance and reduce the regulatory and safety risks. These replace animal-derived cell culture additives with chemically-defined and animal-free alternatives from plant systems, which lead to enhanced performance for optimal stem cell culturing.

How These New Cell Culture Additives Improve Stem Cell Culture

Advantages to using CellastimTM, LacrominTM and OptiferrinTM instead of animal-derived components in stem cell culture medium:

  • Eliminates animal-derived additives-safe and regulatory friendly
  • Proven effective in enhancing stem cell growth inembryonic, mesenchymal, neural, cardiac, liver, kidney, osteoblast, keratinocyte and fibroblast stem cell lines

    Keratinocyte-Proliferation


    Fibroblast-Proliferation

• Maintains stem cells in an undifferentiated state

• Eliminates coating of culture plates for adherent cell lines

• Provides well-defined and consistent stem cell medium

CellastimTM outperforms BSA, HSA and other sources of recombinant albumin in promoting stem cell growth. It is more consistent than other animal-free products, performing similarly to FBS.

LacrominTM is a multi-functional growth factor and protein that provides unique benefits for stem cell research and regenerative medicine applications.

OptiferrinTM is a recombinant human transferrin made in a plant system, so that it is an animal-free source of iron for cell cultures.

Learn More About These Products

For more information on CellastimTM, LacrominTM or OptiferrinTM, including product specifications and pricing, click below.

Click here to see more about CellastimTM.


Click here to see more about LacrominTM.


Click here to see more about OptiferrinTM.

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A rice-derived recombinant human lactoferrin stimulates fibroblast proliferation, migration, and sustains cell survival
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