Zap-CHO – Cell culture media supplement specifically designed for CHO cells.

Zap-CHO can improve the growth and productivity of CHO cells across different phases of cell culture.

Zap-CHO is a powerful Chinese hamster ovary (CHO) cell culture media supplement designed to improve CHO growth and productivity. Zap-CHO is an innovative supplement that has the ability to regulate cell signaling and nutrient delivery. By utilizing cell signaling, Zap-CHO is a powerful growth stimulator that is an excellent replacement for more expensive IGF. While not a nutrient itself, Zap-CHO ensures optimal nutrient delivery, thus maximizing cell productivity. For many applications including cell line development and seed train expansion, Zap-CHO can replace or reduce fetal bovine serum (FBS) without a decrease in productivity.

Zap-CHO provides an important opportunity to maximize performance throughout CHO cell culture production, from cell cloning and selection to expansion and finally commercial manufacturing. Zap-CHO improves chemically defined media performance, while maintaining a defined, animal-free media. As a recombinant product, Zap-CHO provides consistent performance compared to animal derived supplements and can improve the consistency of undefined supplements such as plant hydrolysates. Zap-CHO is a very cost-effective way to quickly maximize your CHO cell culture performance.

Advantages:

• Cost-effective, simple solution to maximize CHO growth and productivity
• Consistent and defined
• Animal-free, regulatory friendly
• Replaces FBS in cell line development and seed train expansion with similar performance
• Benefits shown in many types of media including: classical, serum-free, animal-free, chemically defined

Zap-CHO Cell Culture Media Comparisons

Cells grew to higher density and survived longer in commercial media when supplemented with Zap-CHO. Similar growth kinetics were seen with other leading commercial medias supplemented with Zap-CHO.

Increase in productivity of CHO cells grown in 5 leading commercial medias (A-E) supplemented with Zap-CHO and 10% FBS. Zap-CHO supplemented media gave higher productivity than 10% FBS in all cases. (Commercial Media normalized to 100)

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